Nicolaus Copernicus was a Renaissance- and Reformation-era mathematician and astronomer who formulated a model of the universe that placed the Sun rather than the Earth at the center of the universe, likely independently of Aristarchus of S...

Shah Ismail I, was the founder of the Safavid dynasty of Iran, ruling from 1501 to 23 May 1524 as shah (king). The rule of Ismail is one of the most vital in the history of Iran—before his accession in 1501, Iran, since its occupation by...

Francisco Álvarez de Toledo, Count of Oropesa, was Spanish viceroy of Peru from November 26, 1569 to September 23, 1581. Toledo became the fifth viceroy of Peru in 1569. He was appointed viceroy by Philip II after serving as a steward in th...

Henry II was King of France from 31 March 1547, until his death in 1559. Henry was born in the royal Château de Saint-Germain-en-Laye, near Paris, the son of Francis I and Claude, Duchess of Brittany (daughter of Louis XII of France and Ann...

Carolus Clusius, or Charles de l'Écluse, was a Flemish doctor and pioneering botanist, perhaps the most influential of all 16th century scientific horticulturists. In 1573 he was appointed prefect of the imperial medical garden in Vienna by...

John Dee was a noted British mathematician, astronomer, astrologer, geographer, and consultant to Queen Elizabeth I. He also devoted much of his life to alchemy, divination, and Hermetic philosophy. Dee straddled the worlds of science and...

Anna van Egmont was a wealthy Dutch heiress who became the first wife of William the Silent, Prince of Orange. As the only child of Maximiliaan van Egmond and Françoise de Lannoy, she was suo jure Countess of Buren and Lady of Egmond. She w...

Luis de Velasco, marqués de Salinas (known as Luis de Velasco, hijo to distinguish him from his father), Spanish nobleman, son of the second viceroy of New Spain, and himself the eighth viceroy. He governed from January 27, 1590 to November...

Alessandro Valignano was a Jesuit missionary born in Chieti, back then part of the Kingdom of Naples, who helped supervise the introduction of Catholicism to the Far East, and especially to Japan. Valignano founded the St. Paul's Jesuit col...

Joseph Justus Scaliger was considered to be the foremost scholar in sixteenth-century Europe, referred to as "the light of the world", "the sea of sciences" and similar epithets, and it is to him that we owe a "modern" definition of chronol...

Tokugawa Ieyasu was the founder and first shogun of the Tokugawa shogunate of Japan, which ruled from the Battle of Sekigahara in 1600 until the Meiji Restoration in 1868. Ieyasu seized power in 1600, received appointment as shogun in 1603,...

William Gilbert, also known as Gilberd, was an English physician, physicist and natural philosopher. He was an early Copernican, and passionately rejected both the prevailing Aristotelian philosophy and the Scholastic method of university t...

Tycho Brahe was born in Skane, then in Denmark, now in Sweden. His contributions to astronomy were enormous. He not only designed and built instruments, he also calibrated them and checked their accuracy periodically. He thus revolutionized...

Johan van Oldenbarnevelt was a Dutch statesman, who played an important role in the Dutch struggle for independence from Spain. In 1586, Van Oldenbarnevelt was made Land's Advocate of the province of Holland, an office he held for 32 ye...

Born at Bruges in 1548; died at Leyden in 1620. He was for some years book-keeper in a business house at Antwerp; later he secured employment in the administration of the Franc of Bruges. After visiting Prussia, Poland, Sweden, and Norway h...