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Louis Pasteur, Germ Theory of Disease
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1822
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1895
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Louis Pasteur, Germ Theory of Disease > 
Louis Pasteur was born on December 27, 1822 in Dole, in the region of Jura, France. His discovery that most infectious diseases are caused by germs, known as the "germ theory of disease", is one of the most important in medical history. His work became the foundation for the science of microbiology, and a cornerstone of modern medicine. Pasteur's phenomenal contributions to microbiology and medicine can be summarized as follows. First, he championed changes in hospital practices to minimize the spread of disease by microbes. Second, he discovered that weakened forms of a microbe could be used as an immunization against more virulent forms of the microbe. Third, Pasteur found that rabies was transmitted by agents so small they could not be seen under a microscope, thus revealing the world of viruses. As a result he developed techniques to vaccinate dogs against rabies, and to treat humans bitten by rabid dogs. And fourth, Pasteur developed "pasteurization", a process by which harmful microbes in perishable food products are destroyed using heat, without destroying the food. Each discovery in the body of Pasteur's work represents a link in an uninterrupted chain, beginning with molecular asymmetry and ending with his rabies prophylaxis, by way of his research in fermentation, silkworm, wine and beer diseases, asepsis and vaccines.
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Heinrich Hermann Robert Koch was a German physician. He became famous for isolating Bacillus anthracis (1877), the Tuberculosis bacillus (1882) and the Vibrio cholera (1883) and for his development o... |
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